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Donna S Shewach Selected Research

2- amino- 1,9- dihydro- 9- (3- hydroxy- 4- (hydroxymethyl)cyclopentyl)- 6H- purine- 6- one

2/2010Alteration of the carbohydrate for deoxyguanosine analogs markedly changes DNA replication fidelity, cell cycle progression and cytotoxicity.
3/2002Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells.

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Donna S Shewach Research Topics

Disease

16Neoplasms (Cancer)
01/2017 - 03/2002
4Carcinoma (Carcinomatosis)
03/2006 - 08/2002
3Breast Neoplasms (Breast Cancer)
11/2016 - 04/2004
3Melanoma (Melanoma, Malignant)
10/2013 - 08/2008
2Liver Neoplasms (Liver Cancer)
10/2013 - 06/2011
1Retinoblastoma (Glioblastoma, Retinal)
01/2013
1Colonic Neoplasms (Colon Cancer)
12/2012
1Genomic Instability
04/2011
1Carcinogenesis
04/2011
1Weight Loss (Weight Reduction)
12/2005
1Turcot syndrome
10/2003
1Glioblastoma (Glioblastoma Multiforme)
10/2003

Drug/Important Bio-Agent (IBA)

7GemcitabineFDA Link
11/2016 - 10/2003
6DNA (Deoxyribonucleic Acid)IBA
11/2016 - 10/2003
4Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
01/2015 - 10/2003
4Ganciclovir (Cytovene)FDA LinkGeneric
12/2013 - 03/2002
4Pharmaceutical PreparationsIBA
12/2013 - 04/2004
3NucleosidesIBA
12/2013 - 02/2010
3NucleotidesIBA
10/2013 - 08/2008
2DeoxyribonucleosidesIBA
01/2017 - 01/2013
2triphosphoric acid (triphosphate)IBA
01/2015 - 12/2012
2AcetylgalactosamineIBA
10/2013 - 06/2011
2Peptides (Polypeptides)IBA
10/2013 - 06/2011
2Dendrimers (Dendrons)IBA
10/2013 - 06/2011
25-fluoro-2'-deoxyuridineIBA
12/2012 - 09/2008
2Small Interfering RNA (siRNA)IBA
12/2012 - 08/2008
22- amino- 1,9- dihydro- 9- (3- hydroxy- 4- (hydroxymethyl)cyclopentyl)- 6H- purine- 6- oneIBA
02/2010 - 03/2002
2ProdrugsIBA
03/2006 - 03/2002
1Folic Acid (Vitamin M)FDA LinkGeneric
09/2015
12'-deoxyadenosineIBA
01/2015
1rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA
10/2013
1purineIBA
10/2013
1EnzymesIBA
10/2013
1GuanosineIBA
10/2013
1Guanosine Triphosphate (GTP)IBA
10/2013
1Purine NucleotidesIBA
10/2013
1GMP ReductaseIBA
10/2013
1SugarsIBA
10/2013
1LigandsIBA
10/2013
1Blood Proteins (Serum Proteins)IBA
10/2013
1AcidsIBA
10/2013
1Histones (Histone)IBA
01/2013
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2013
1Lysine (L-Lysine)FDA Link
01/2013
1ChromatinIBA
01/2013
1Thymidylate SynthaseIBA
12/2012
1Culture MediaIBA
12/2012
1Poly(amidoamine)IBA
06/2011
1Asialoglycoprotein ReceptorIBA
06/2011
1ThioureaIBA
06/2011
1penciclovir (Denavir)FDA Link
02/2010
1DeoxyguanosineIBA
02/2010
1Antineoplastic Agents (Antineoplastics)IBA
09/2008
1Proteins (Proteins, Gene)FDA Link
08/2008
1AntimetabolitesIBA
09/2007
1Flucytosine (Ancobon)FDA Link
03/2006
1Docetaxel (Taxotere)FDA Link
04/2004
1DeoxycytidineIBA
10/2003
1Complementary DNA (cDNA)IBA
10/2003
1Diphosphates (Pyrophosphates)IBA
10/2003
1Hydroxyurea (Hydrea)FDA LinkGeneric
10/2003
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
10/2003
1AphidicolinIBA
10/2003
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
08/2002
1Connexin 43 (Connexin43)IBA
08/2002
1ConnexinsIBA
08/2002
1Doxorubicin (Adriamycin)FDA LinkGeneric
08/2002
1Thymidine KinaseIBA
03/2002

Therapy/Procedure

1Aftercare (After-Treatment)
11/2016
1Chemoradiotherapy
11/2016
1Transjugular Intrahepatic Portasystemic Shunt
10/2013
1Radiotherapy
05/2004